According to a statement released by NDS, the Special Forces of the Directorate were on their way to Helmand when they were ambushed in the vicinity of Farah province.
The statement furhter added that the NDS Special Forces responded to the ambush, leaving at least sixteen militants dead.
The National Directorate of Security (NDS) also added that some weapons and munitions belonging to the Taliban militants were also confiscated following the clash.
The anti-government armed militant groups including Taliban militants have not commented regarding the report so far.
Both Farah and Helmand are among the relatively volatile provinces in the Western and Southern parts of the country.
This comes as the Taliban militants suffered heavy casualties during the Afghan and US forces raids after a failed attack on Farah city last month.