The Ministry of Defense (MoD) said the operations were jointly conducted by the Afghan security forces and with the support of the Afghan Air Force.
According to a statement by MoD, the operations were conducted in Greshk district of Helmand and some weapons and explosives belonging to the militants were also destroyed.
The statement by MoD further added that five militants were killed in a separate operation in Sar-e-Hawza district of southeastern Paktika province.
The anti-government armed militant groups have not commented regarding the report so far.
Helmand is among the relatively volatile provinces in southern Afghanistan where anti-government armed militant groups are actively operating and frequently carry out insurgency activities.
The Taliban group launched a major attack on various security posts of the Afghan security forces late last month but the attacks were repulsed with the deployment of additional forces.