According to reports four members of one family were killed in Ghor province on Thursday morning, local officials told the media.
A spokesman for the governor of Ghor Zalmay Karimi told the media that the incident happened in village Kharistan near Firuzkoh, the provincial capital.
No group including the Taliban has claimed responsibility for the explosion.
This comes as 4 civilians were killed in a roadside bomb blast in the village of Barakhana in the outskirts of Firuzkoh.
While on Monday, three civilians were murdered on Ghor-Herat highway.
Reports indicated that these civilians were killed in the Band-e-Bain area of Ghor-Herat highway.
Officials have accused the Taliban for being involved in murdering the three civilians.