The riot reportedly erupted after a refugee tore pages from the Holy Quran prompting anger of some 20 other residents in the refugee center in Suhl city of Thuringen State on Wednesday evening.
Police say the confrontation escalated into a riot and around 100 refugees took part in it.
125 police officers were dispatched to the area to break the brawl but they also came under the attack from refugees and were pelted with sticks and stones.
Four police officers, two badly, and 11 refugees were wounded in the clash.
Seven police vehicles were also damaged during the riot that took around four hours to come under control.
According to the officials, the person who tore pages from the Holy Quran had arrived from Afghanistan. Police took him into custody for his own safety.