According to local authorities, the airstrike was carried in Khas Kunar district.
Provincial security chief, Gen. Abdul Habib Syed Khel, said at least four Pakistani militants were also among the ten militants killed following the drone strike.
The anti-government armed militant groups have not commented regarding the report so far.
Kunar is among the volatile provinces in eastern Afghanistan which shares a border with the tribal regions of Pakistan.
The anti-government armed militant groups including Pakistani militants are actively operating in its various districts and frequently carry out insurgency activities.