Defense Ministry spokesman, Gen. Zahir Azimi, said the militants were killed during operations in eight different provinces.
Gen. Azimi further added at least 66 Taliban militants were killed and 41 others were injured during the operations, and 16 others were arrested.
He said Afghan Natioal Army (ANA) forces also confiscated various types of weapons, ammunitio and explosives including 58 rounds Improvised Explosive Device (IED) durig the operations.
In the meantime, the Ministry of Interior (MoI) said at least 18 Taliban militants were killed during the operations in the past 24 hours.
MoI said the operations were jointly conducted by Afghan police, army and intelligence forces in Kunar, Nangarhar, Faryab, Kandahar, Zabul, Uruzgan and Logar provinces.
The Taliban militants group has not commented regarding the report so far.