According to local government officials, the incident took place on Monday morning in Nerkh district, leaving four police officers dead and 19 others injured.
Provincial governor spokesman Ataullah Khogyani confirming the report said the explosion took place near the district security commandment.
Mr. Khogyani confirmed that four policemen were killed and 19 others were injured following the blast.
He also added that the death toll could rise as the health condition of a number of police officers inujured in the blast is critical.
According to Ataullah Khogyani, the blast also incurred damage to district security compound and the surrounding properties.
No group including the Taliban militants has so far claimed responsibility behind the incident.