The incident took place in eastern Ghazni city after explosives packed in a cycle went off in old market area.
Eye witnesses in the area said at least two people including a woman and a man were injured following the blast.
Provincial governor spokesman Fazal Sabawon confirming the report said the main target of the explosion was an Afghan intelligence official.
He confirmed at least two Afgan civilians along with an Afghan intelligence officer were injured following the blast.
No group has so far claimed responsibility behind the incident.