Hazrat Hussain Mashriqiwal, spokesman for Nangarhar police headquarters confirms the report.
Mashriqiwal said the attack took place in Farsh area of the district last night.
He added that the insurgents killed were involved in terrorist activities in Marko Bazaar area of the district.
He confirmed that there were no civilian casualties in the attack.
This was the 3rd drone strike on Sunday.
Eight insurgents killed in different drone strikes in Kapisa and Nuristan provinces.