The incident took place close to the provincial capital late on Monday after a civilian vehicle struck a roadside mine.
The provincial government media office in a statement said the explosion ripped through the vehicle in Choni area at around 8 pm local time on Monday.
The statement further added that the blast targeted a mini truck leaving two civilians dead and one wounded.
The local security and police officials have launched an investigation in connection to the incident, the provincial police commandment added.
The anti-government armed militant groups frequently use explosives materials for the roadside bombings and car bombings to target the government staff and security personnel.
However, in majority of such incidents the ordinary civilians are targeted besides such bombings incur casualties to the security personnel and in some cases the Taliban militants themselves are killed or wounded.
A total of 10,453 civilian casualties – 3,438 people killed and 7,015 injured – were documented in the 2017 Annual Report released last month by the UN Assistance Mission in Afghanistan (UNAMA) and the UN Human Rights Office.
The report further added that the high number of casualties to the civilians were inflicted by suicide bombings and other attacks using improvised explosive devices (IEDs).