Ebadullah Karimi, spokesman for Kabul police while confirming the incident said that the suicide bomber was driving a vehicle laden with explosions who rammed to the wall of the Paghman police HQ.
Four people including head of the Criminal Investigation Department (CID) of Paghman District were killed and 41 others, most of them civilians, wounded in the explosion.
Soon after the incident security forces cordoned off the area and transferred those wounded to nearby medical facilities.
The death toll may rise as doctors have announced some of the victims being in critical condition.
No group had claimed responsibility for the explosion by the time this report was filed.