The provincial police commandment said late on Sunday that the airstrike was carried out in Dai Chupan Khak Afghan district.
According to the security officials, at least 7 ISIS militants including a commander of the group were also wounded in the airstrike.
The anti-government armed militant groups including the ISIS loyalist have not commented regarding the report so far.
This comes as Chief Executive Abdullah Abdullah said late in December last year that special military operations will kick off soon in southeastern Ghazni and southern Zabul provinces to suppress the loyalists of the Islamic State of Iraq and Syria (ISIS) terrorist group and Taliban insurgents.
He made the remarks during a meeting with the elders of the two provinces which organized amid concerns that the fighters of the two group are attempting to expand foothold in some districts of the two provinces.
The elders of Zabul said the local residents in Khak-e-Afghan and Nawbahar districts have noted movements of the two groups to establish and strengthen their presence.
The Ghazni representatives also said the ISIS loyalists and Taliban insurgents have started to expand their foothold in Nawa district.
The ISIS militants have reportedly arrived with their families and are fully equipped with the area turning into an entry point for the foreign insurgents.