The Ministry of Defense (MoD) said the operations were jointly conducted by Afghan Army and security forces from the other institutions, including the Afghan Air Force.
According to an operational update by MoD, at least 12 militants were also wounded and 12 more were arrested by the security forces during the operations.
At least 6 of the militants were killed in air and ground raids in Charchino district of Uruzgan province, MoD said, adding that 5 more were killed in Atghar district of Zabul.
The update further added that 4 militants were killed and 8 others were wounded during a separate operation in Kunduz.
The Afghan forces also killed militants during separate operations conducted in Kandahar, Helmand and Khost provinces, MoD added.
According to MoD, at least 9 Afghan soldiers also lost their lives during the operations conducted to suppress the insurgency activities of the internal and external terror groups.