The 203rd Thunder Corps of the Afghan Military in the Southeast said the airstrikes were carried out in Khogyani and Nawa districts of the province.
According to a statement released by 203rd Thunder Corps, the militants were targeted in Arzo area of Khogyani and Langa area of Nawa districts.
The statement further added that 21 militants were killed and at least 10 others were wounded during the same airstrikes.
The 203rd Thunder Corps also added that the Afghan forces discovered and defused 9 improvised explosive devices dring the opertions in Andar and Maidan Wardak provinces.
The anti-government armed militant groups including Taliban militants have not commented regarding the report so far.
Ghazni is among the relatively volatile provinces in southeastern parts of the country where the Taliban militants and terrorist belonging to the other groups are actively operating in some of its districts.
The Taliban militants launched a coordinated attack on Ghazni city earlier last month, sparking heavy clashes that lasted for several days before the militants were driven out of the city.