The 201st Silab Corps of the Afghan Military in the East said the latest airstrikes were carried out in the vicinity of Achin district.
According to the Silab Corps, the militants were targeted in Mamand Dara area of the district and as a result at least 25 insurgents were killed.
The anti-government armed militant groups including the ISIS insurgents have not commented regarding the report so far.
This comes as the local officials said Saturday at least three ISIS militants were killed in drone strikes in this province.
The officials further added that the airstrikes were carried out by the unmanned aerial vehicles of the US forces in Haska Mina district.
According to the officials, some weapons, ammunition, and explosives of the terror group were also eliminated during the airstrikes.
Earlier, the 201st Silab Corp had said that nine ISIS militants were killed during the air and ground operations in Achin district.