The Ministry of Defense (MoD) said at least 21 militants of the terror group were also wounded in the explosion.
A statement by MoD said the militants were looking to transport an explosive device from Mazdaki area of Achin district to Shedil Bazar of the same district when the explosives went off prematurely.
The loyalists of the ISIS terrorist group are attemtping to continue to their insurgency activities despite the terror group suffered setbacks during the recent months as a result of the coordinated military operations.
The provincial officials in Nangarhar province announced earlier this month that the counter-terrorism operations to suppress the activities of the terror group concluded after 21 days.
The officials further added nearly 300 loyalists of the terror group were killed or wounded during the operations.
The operations were launched by the Afghan security forces amid concerns that the loyalists of the terror group are establishing a regional operational base as they were attempting to consolidate operations with the terror group in Syria and Iraq.
The coalition officials estimated around 1,000 to 3,000 Islamic State fighters are stationed in in eastern Afghanistan and are trying to establish a base of operations in the rugged mountains of Nangahar Province.